Fine Chemicals - Cynoacetamide
  • Adjuvant
  • Crop Care Silicones
  • Antifoaming Agent
  • Benzotriazole
  • 2-Chloroacetamide
  • Cyanoacetamide
  • Cyanoacetamide

    Nitrile is any of a family of organic compounds containing cyano group (-C¡ÕN)

    which is attached to a carbon atom and having the general formula RC¡ÕN.

    Their names are corresponding to carboxylic acids by changing '-ic acid'

    to '-onitrile', or '-nitrile', whichever preserves a single letter o.

    Examples are acetonitrile from acetic acid and benzonitrile from benzoic acid.

    Pendant nitriles are often named as ¡°cyano¡± substituents. Cyanoacetic acid,

    the half nitriled-malonic acid, and its esters are basic chemical intermediates

    for the production of;

    • Malonates
    • Barbitals
    • Caffeine, Betaine, Vitamin B
    • Pharamceuticals
    • Glycine
    • Surfactancts
    • Agrochemicals
    • Dyestuffs
    • Adhesives
    • Indigo dyes
    • Herbicides
    • Engineering plastics

    Although nitriles don't have a carbonyl group, they are often considered as derivatives of carboxylic acids. Nitrile undergoes acid hydrolysis to form a carboxylic acid. Nitrile is reduced to form amine in the presence of nickel catalyst. Grignard reagents add to nitriles, forming a relatively stable imino derivative which can be hydrolyzed to a ketone.

    Metaloimine is hydrolyzed to give beta-ketoester. Nitrile undergoes a sequence of nucleophilic additions with an alcohol under acid catalysis, called nitrile alcoholysis. Nitriles are hydrolyzed to carboxylic acids, alcoholyzed to esters, reduced to amines, cyclyzed to pyridine derivatives.